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Recommendation and Guideline
Local ablation for hepatocellular carcinoma: 2024 expert consensus-based practical recommendation of the Korean Liver Cancer Association
Seungchul Han, Pil Soo Sung, Soo Young Park, Jin Woong Kim, Hyun Pyo Hong, Jung-Hee Yoon, Dong Jin Chung, Joon Ho Kwon, Sanghyeok Lim, Jae Hyun Kim, Seung Kak Shin, Tae Hyung Kim, Dong Ho Lee, Jong Young Choi
J Liver Cancer. 2024;24(2):131-144.   Published online August 30, 2024
DOI: https://doi.org/10.17998/jlc.2024.08.04
  • 23,217 Views
  • 643 Downloads
  • 12 Web of Science
  • 12 Citations
AbstractAbstract PDFSupplementary Material
Local ablation for hepatocellular carcinoma (HCC), a non-surgical option that directly targets and destroys tumor cells, has advanced significantly since the 1990s. Therapies with different energy sources, such as radiofrequency ablation, microwave ablation, and cryoablation, employ different mechanisms to induce tumor necrosis. The precision, safety, and effectiveness of these therapies have increased with advances in guiding technologies and device improvements. Consequently, local ablation has become the firstline treatment for early-stage HCC. The lack of organized evidence and expert opinions regarding patient selection, pre-procedure preparation, procedural methods, swift post-treatment evaluation, and follow-up has resulted in clinicians following varied practices. Therefore, an expert consensus-based practical recommendation for local ablation was developed by a group of experts in radiology and hepatology from the Research Committee of the Korean Liver Cancer Association in collaboration with the Korean Society of Image-guided Tumor Ablation to provide useful information and guidance for performing local ablation and for the pre- and posttreatment management of patients.

Citations

Citations to this article as recorded by  
  • Taiwan Academy of Tumor Ablation (TATA) consensus on hepatocellular carcinoma ablation
    Ching-Wei Chang, Ming-Shun Wu, Wei-Yu Kao, Ming-Feng Chiang, Shih-Jer Hsu, Shen-Yung Wang, Chao-Hung Hung, Chih Horng Wu, San-Chi Chen, Yu-Ming Cheng, I-Cheng Lee, Yi-Chung Hsieh, Wei-Ting Chen, Chen-Chun Lin, Po-Chin Liang, Jen-I. Hwang, Shi-Ming Lin, Ka
    Hepatology International.2026; 20(2): 240.     CrossRef
  • Improved Detection of Small (<2 cm) Hepatocellular Carcinoma via Deep Learning-Based Synthetic CT Hepatic Arteriography: A Multi-Center External Validation Study
    Jung Won Kwak, Sung Bum Cho, Ki Choon Sim, Jeong Woo Kim, In Young Choi, Yongwon Cho
    Diagnostics.2026; 16(2): 343.     CrossRef
  • Application of different energy ablations in the treatment of solid tumors
    Liangliang Meng, Xiao Zhang, Xiaobo Zhang, YingtianWei, Yueyong Xiao
    Med-X.2026;[Epub]     CrossRef
  • Liver resection versus radiofrequency ablation or transarterial chemoembolization for early multinodular BCLC-A hepatocellular carcinoma: a systematic review and meta-analysis
    Maria F. F. Viana, Arthur A. Braga, Lucas B. Carvalho, Danilo C. M. S. Vasconcellos, Bianca C. M. R. Alexandrino, Felipe J. F. Coimbra
    Journal of Liver Cancer.2026; 26(1): 157.     CrossRef
  • Microwave ablation vs. liver resection for patients with hepatocellular carcinomas
    Hyundam Gu, Yeonjoo Seo, Dong Jin Chung, Kwang Yeol Paik, Seung Kew Yoon, Jihye Lim
    Journal of Liver Cancer.2025; 25(1): 99.     CrossRef
  • Evolving trends in epidemiology, etiology, and treatment patterns for hepatocellular carcinoma in South Korea
    Soo Young Hwang, Ju Dong Yang
    Journal of Liver Cancer.2025; 25(1): 4.     CrossRef
  • Efficacy and safety of ultrasound-guided percutaneous microwave ablation for hepatocellular carcinoma at specific anatomic sites of the liver: a systematic review and meta-analysis
    Jiandong Zha, Fang Zhang, Tuoyu Cao, Shasha Li, Xuelian Shen, Liangliang Xu, Wenqi Chen
    Frontiers in Surgery.2025;[Epub]     CrossRef
  • Efficacy and safety of ultrasound-guided percutaneous microwave ablation for hepatocellular carcinoma at specific anatomic sites of the liver: a systematic review and meta-analysis
    Yongsheng Fu, Qicong Zhu, Xin Zhao, Jingfen Lu, Wei Wang
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • Immunotherapy in GI Cancers: Lessons from Key Trials and Future Clinical Applications
    Supriya Peshin, Faizan Bashir, Naga Anvesh Kodali, Adit Dharia, Sajida Zaiter, Sakshi Singal, Nagaishwarya Moka
    Antibodies.2025; 14(3): 58.     CrossRef
  • Liver Cancer: Artificial Intelligence (AI)-Based Integrated Therapeutic Approaches
    Mythileeswari Lakshmikanthan, Sakthivel Muthu, John T. D. Caleb, Yuvaraj Maria Francis, Indra Neel Pulidindi
    Bioengineering.2025; 12(8): 837.     CrossRef
  • Asian Conference on Tumor Ablation Guidelines for Hepatocellular Carcinoma
    Shuichiro Shiina, Ryosuke Tateishi, Joon Il Choi, So Yeon Kim, Zhiqiang Meng, Lujun Shen, Sheng-Nan Lu, Jen-I. Hwang, Maki Tobari, Hitoshi Maruyama, Terguunbileg Batsaikhan, Qing Deng, Lariza Marie Canseco, Yoshinari Asaoka, Shi-Ming Lin, Kai-Wen Huang, H
    Liver Cancer.2025; 14(5): 651.     CrossRef
  • Practical consensus multi-specialty guidelines on image-guided ablation for hepatocellular carcinoma
    David S. Lu
    Journal of Liver Cancer.2024; 24(2): 120.     CrossRef
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Review Article
Directions for Future Hepatocellular Carcinoma Treatment Guidelines; Hepatologist’s Perspective: Systemic Approach to Multidisciplinary Treatment
Soo Young Park, Won Young Tak
Journal of the Korean Liver Cancer Study Group. 2013;13(1):8-13.   Published online February 28, 2013
DOI: https://doi.org/10.17998/jlc.13.1.8
  • 1,960 Views
  • 7 Downloads
AbstractAbstract PDF
Hepatocellular carcinoma is one of the most important malignancies in Korea with high mortality rates. Although current guidelines define treatment algorithm by performance status, underlying liver function, size and number of hepatocellular carcinoma, those are not fully reflect the complexities of patients’ characteristics and recently advanced available therapeutic options. Treatment can be optimized by available therapeutic options based on the patients’ characteristics. Because of the heterogeneity in presentation among patients, it is now widely accepted that management of hepatocellular carcinoma requires multimodality and multidisciplinary treatment approaches involving hepatologists, surgeons, interventional radiologists, and radiation oncologists. These approaches are important in improving the survival of patients with hepatocellular carcinoma.
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